Cisplatin and electrolyte abnormalities

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August undefined, 2024

WebIn patients with gynecologic cancers, treated with cisplatin or cisplatin in combination with paclitaxel, a higher incidence of nephrotoxicity in the combination group was noted. 414 In addition, ... Electrolyte abnormalities that may either increase the toxicity of concomitant agents (hypokalemia in patients receiving digoxin) or may be ... WebMay 18, 2024 · Compared with young patients, the incidences of cisplatin-induced nephrotoxicity and acute kidney injury (AKI) in elderly patients are significantly increased, …

Gitelman-like syndrome after cisplatin therapy: a case report and ...

WebMay 24, 2006 · This drug should be considered among the possible causes of chronic unexplained electrolyte disorders. Cisplatin is a well-known nephrotoxic antineoplastic … WebSep 18, 2024 · NCBI Bookshelf crystal art art software phone number

Lithium concentrations during cisplatin-based chemotherapy …

WebDec 15, 2024 · An electrolyte imbalance occurs when your body’s mineral levels are too high or too low. This can negatively affect vital body systems. Electrolytes must be evenly balanced for your body to... WebCertain medications may cause an electrolyte imbalance such as: Chemotherapy drugs (cisplatin) Diuretics (furosemide [Lasix] or bumetanide [Bumex]) Antibiotics (amphotericin B) Corticosteroids (hydrocortisone) Symptoms of Electrolyte Imbalance: As described, an electrolyte imbalance may create a number of symptoms. WebMay 24, 2006 · Conclusion: Cisplatin can cause permanent nephrotoxicity, including Gitelman-like syndrome. This drug should be considered among the possible causes of chronic unexplained electrolyte disorders. Publication types Case Reports Review MeSH terms Adult Alkalosis / chemically induced* Antineoplastic Agents / adverse effects* dutchmar sailcase boom

Electrolyte Disorders in Cancer Patients SpringerLink

Hypomagnesemia - Endocrine and Metabolic Disorders - Merck …

WebAbstract Cisplatin is a widely used platinum‐based chemotherapy agent. Its common adverse effects are neuropathy, nephrotoxicity, electrolyte abnormality, and rarely causing thrombotic vascular toxicity. We present a patient known to have small‐cell lung cancer who developed ischemic cerebrovascular accident (CVA) after receiving ... WebAug 26, 2024 · Electrolyte disturbances can be caused by infections, medicines, trauma and surgery; poor nutritional intake and malabsorption can also contribute to deficiencies [3] . The exact incidence of electrolyte disturbances in the UK is difficult to define, as individual studies have tended to focus on the occurrence in discrete populations [4,5] . dutchmark roofingWebJan 1, 2015 · Similarly, hypomagnesemia exclusive to chemotherapeutic agents like cisplatin, ifosfamide, and cetuximab is only seen in cancer patients. This chapter describes the frequency of the most commonly observed electrolyte disorders in the oncology patient and delves into the unique cancer- or chemotherapy-related etiology of these … crystal art accessory kit

"WebApr 12, 2024 · In cancer patients, electrolyte disorders are frequent due to tubular functional abnormalities related to chemotherapeutic drugs, the TLS and the impaired secretion of antidiuretic hormone ... As previously described, also the cisplatin can induce electrolyte imbalances. In this case, the standard approach to avoid cisplatin-induced ... " - Cisplatin and electrolyte abnormalities

Cisplatin and electrolyte abnormalities

Gitelman-like syndrome after cisplatin therapy: a case report and ...

WebNov 1, 2024 · Platinum chemotherapy, particularly cisplatin, is commonly associated with electrolyte imbalances, including hypomagnesemia, hypokalemia, hypophosphatemia, hypocalcemia and hyponatremia. WebJun 24, 2024 · Electrolyte abnormalities (hypokalemia, hypophosphatemia, and hypomagnesemia) Electrolyte abnormalities were defined as ≥ grade 1 hypokalemia, …

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WebCisplatin is a coordinate metal complex with significant antineoplastic activity and various effects, including acute anc chronic renal insufficiency and renal magnesium wasting. … WebA slight electrolyte imbalance may not cause noticeable changes. When problems occur, you may experience: Confusion and irritability. Diarrhea or constipation. Fatigue. Headaches. Irregular or fast heart rate (arrhythmia). Muscle cramps, muscle spasms or weakness. Nausea and vomiting. Numbness or tingling in limbs, fingers and toes.

WebMay 1, 2024 · The most common diagnoses were central nervous system tumors (58 [36%]), neuroblastoma (43 [27%]), and osteosarcoma (33 [21%]). Acute kidney injury (by serum creatinine level increase) occurred in 48 of 159 patients (30%) at early cisplatin infusions and 23 of 143 patients (16%) at late cisplatin infusions. WebNational Center for Biotechnology Information

WebAug 18, 2024 · Mannitol, given as a hypertonic solution, is primarily used in the treatment of cerebral edema and glaucoma. Although generally well tolerated, a variety of fluid, electrolyte, and kidney complications can occur if the patient is not carefully monitored. (See "Evaluation and management of elevated intracranial pressure in adults", section on ...

WebBlood test results showing low levels may lead to: irregular heartbeat, confusion, blood pressure changes, nervous system or bone disorders. Blood test results showing high …

WebJul 18, 2024 · Cisplatin causes hypomagnesemia in a dose-dependent fashion and affects up to 90% of patients if no preventive measures are taken (see Section 5 below). 79 The etiology of cisplatin-induced hypomagnesemia is not completely understood; renal Mg loss is the primary mechanism, but gastrointestinal losses have also been reported. 80 … dutchmans lawn \u0026 garden foley alWebJan 1, 2015 · Cisplatin administration is commonly associated with electrolyte imbalance. Careful monitoring of renal function and serum electrolytes is therefore essential in this setting. dutchmans lane easton mdWebOct 19, 2024 · Severe electrolyte abnormalities during cisplatin were associated with having 2–6-month CKD or hypertension (adjusted odds ratio (AdjOR) [95% CI]: 2.65 [1.04–6.74]). Having both AKI and severe electrolyte abnormalities was associated with 2–6-month hypertension (AdjOR [95% CI]: 3.64 [1.05–12.62]). Conclusions dutchmans meadow hoaWebMar 1, 2024 · A case of an elderly male presenting with significant recurrent hyponatremia, and prerenal azotemia, with recent exposure to cisplatin along with significant hypovolemia and urinary loss of sodium is reported. Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude … crystal art 3d christmas treeWeb• Hypomagnesemia and Accompanying Electrolyte Abnormalities: Monitor during treatment and for at least 8 weeks following the completion. Replete electrolytes as necessary. (5.6) ... and Cisplatin . 5.6 Hypomagnesemia and Accompanying Electrolyte Abnormalities . 5.7 Increased Tumor Progression, Increased Mortality, or Lack ... dutchmans new storeWebcisplatin (Rx) Brand and Other Names: Classes: Antineoplastics, Alkylating; Antineoplastics, Platinum Analog Print Dosing & Uses AdultPediatricGeriatric Dosage … dutchmark gouda cheeseWebelectrolyte imbalance (hyponatremia, hypochloremic alkalosis, hypokalemia, hypomagnesemia ... (with abnormalities of the fasting and 2-hour postprandial sugar) have been observed, and rarely, precipitation of diabetes mellitus has been reported. ... There is a risk of ototoxic effects if cisplatin and LASIX are given concomitantly. In addition, dutchmark smoked gouda