Web摘要:目的 探讨乙酸钠(NaAc)对氧糖剥夺(OGD)损伤后皮质神经元的作用及低氧诱导因子-1α(HIF-1α)表达的影响。方法 将OGD处理的皮质神经元作为脑缺血模型,采用细胞存活实验(CCK-8)、乳酸脱氢酶(LDH)释放实验检测NaAc处理后的神经元存活情况,Western blot方法检测OGD损伤后、NaAc处理后神经元中HIF-1α蛋白 ... Web15 de ago. de 2011 · Published: 15 August 2011; Epigenetic regulation of HIF-1α in renal cancer cells involves HIF-1α/2α binding to a reverse hypoxia-response element. J Xu 1, B Wang 1, Y Xu 1, L Sun 1,
HIF-1 Regulates Iron Homeostasis in Caenorhabditis elegans by ...
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HIF-1α overexpression in mesenchymal stem cell-derived …
WebHypoxia-inducible factor 1 (HIF-1) mediates adaptive responses to reduced oxygen availability by regulating gene expression. A critical cell-autonomous adaptive response … WebHIF é a sigla de uma proteína que se chama “hypoxia-inducible factor”, ou em bom português Fator Induzido por Hipóxia. E como já foi dito é um fator de transcrição, significando, portanto que permite que alguns genes sejam transcritos e se produza determinados RNAs, e, a partir destes, proteínas. Contudo, nos nossos tecidos bem ... Web5 de jan. de 2011 · Hypoxia-inducible factors (HIFs) mediate transcriptional responses to reduced O 2 availability ().HIF-1, the first identified member of the HIF family, is … diamond head ranch